Things to do when this happens:
Add any outside SMTP servers (example: spam filtering systems) and MX record to the Backup MX Hosts due to ratelimits.
Make sure Local Mail Exchanger is been set correctly.
Add MX IPs under the WHM >>> Exim Configuration Manager >>> “Sender verification bypass IP addresses” and “Trusted SMTP IP addresses”
IPs whitelisted under the server csf firewall.